Jumat, 24 Desember 2010

Acinic cell carcinoma

Acinic cell carcinoma

· Account for about 1% of salivary gland tumors

· Show an almost uniform pattern of large cells similar to serous cells,with granular basophillic cytoplasm,often in an acinar arrangement

· Characteristic feature-scattered round 'holes' throughout the entrapted secretion

· Sometimes these are so numerous as to give the tumor a lce like appearance

· Despite,apperantly benign histolological appearances,acinic cell carcinomas can be invasive and metastasise

· More obviously malignant varients with nuclear pleomorphism and hyperchromatism and also occationally seen microscopically.

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